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Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer's disease
Dystrophic neurites (also termed axonal spheroids) are found around amyloid deposits in Alzheimer’s disease (AD), where they …
Yifei Cai
,
Jean Kanyo
,
Rashaun Wilson
,
Shveta Bathla
,
Pablo Leal Cardozo
,
Lei Tong
,
Shanshan Qin
,
Lukas A. Fuentes
,
Iguaracy Pinheiro-De-Sousa
,
Tram Huynh
,
Liyuan Sun
,
Mohammad Shahid Mansuri
,
Zichen Tian
,
Hao-Ran Gan
,
Amber Braker
,
Hoang Kim Trinh
,
Anita Huttner
,
TuKiet T. Lam
,
Evangelia Petsalaki
,
Kristen J. Brennand
,
Angus C. Nairn
,
Jaime Grutzendler
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One nose but two nostrils: Learning to align with sparse connections between two olfactory cortices
Add the full text or supplementary notes for the publication here using Markdown formatting.
Bo Liu
,
Shanshan Qin
,
Venkatesh N. Murthy
,
Yuhai Tu
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Functional imaging and quantification of multineuronal olfactory responses in C. elegans
Many animals perceive odorant molecules by collecting information from ensembles of olfactory neurons, where each neuron uses receptors …
Albert Lin
,
Shanshan Qin
,
Helena Casademunt
,
Min Wu
,
Wesley Hung
,
Gregory Cain
,
Nicolas Z. Tan
,
Raymond Valenzuela
,
Leila Lesanpezeshki
,
Vivek Venkatachalam
,
Cengiz Pehlevan
,
Mei Zhen
,
Aravinthan D. T. Samuel
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Coordinated drift of receptive fields in Hebbian/anti-Hebbian network models during noisy representation learning
Recent experiments have revealed that neural population codes in many brain areas continuously change even when animals have fully …
Shanshan Qin
,
Shiva Farashahi
,
David Lipshutz
,
Anirvan M. Sengupta
,
Dmitri B. Chklovskii
,
Cengiz Pehlevan
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DOI
URL
Drifting neuronal representations: Bug or feature?
The brain displays a remarkable ability to sustain stable memories, allowing animals to execute precise behaviors or recall stimulus …
Paul Masset
,
Shanshan Qin
,
Jacob A. Zavatone-Veth
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Cell-to-cell variability in inducible Caspase9-mediated cell death
iCasp9 suicide gene has been widely used as a promising killing strategy in various cell therapies. However, different cells show …
Yuan Yuan
,
Huixia Ren
,
Yanjun Li
,
Shanshan Qin
,
Xiaojing Yang
,
Chao Tang
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DOI
URL
Short-Term Plasticity Regulates Both Divisive Normalization and Adaptive Responses in Drosophila Olfactory System
In Drosophila, olfactory information received by olfactory receptor neurons (ORNs) is first processed by an incoherent feed forward …
Yuxuan Liu
,
Qianyi Li
,
Chao Tang
,
Shanshan Qin
,
Yuhai Tu
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DOI
URL
Contrastive Similarity Matching for Supervised Learning
We propose a novel biologically plausible solution to the credit assignment problem motivated by observations in the ventral visual …
Shanshan Qin
,
Nayantara Mudur
,
Cengiz Pehlevan
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Internal state configures olfactory behavior and early sensory processing in Drosophila larvae
The first olfactory processing center in the larval Drosophila brain uses information about feeding state to shape behavior. Animals …
Katrin Vogt
,
David M. Zimmerman
,
Matthias Schlichting
,
Luis Hernandez-Nunez
,
Shanshan Qin
,
Karen Malacon
,
Michael Rosbash
,
Cengiz Pehlevan
,
Albert Cardona
,
Aravinthan D. T. Samuel
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DOI
URL
Optimal compressed sensing strategies for an array of nonlinear olfactory receptor neurons with and without spontaneous activity
There are numerous different odorant molecules in nature but only a relatively small number of olfactory receptor neurons (ORNs) in …
Shanshan Qin
,
Qianyi Li
,
Chao Tang
,
Yuhai Tu
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